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papers

The effect of pelvic fractures on future stress incontinence and pelvic organ prolapse surgery

Published: February 6, 2015
Category: Papers
Authors: Al-Hothi H, Chou Q, Lawendy AR, MacMillan B, Welk B, Winick-Ng J
Country: Canada
Language: null
Type: Population Health
Settings: Hospital, PCP

Int Urogynecol J

Western University, London, ON, Canad

INTRODUCTION AND HYPOTHESIS: Pelvic fractures in women significantly disrupt the pelvic floor, which may cause stress urinary incontinence (SUI) or pelvic organ prolapse (POP). Our objective was to assess the incidence of operative treatment for SUI and POP after pelvic fracture.

METHODS: We used administrative data from Ontario, Canada, to conduct a retrospective cohort study. Female patients who underwent operative repair of a pelvic fracture between 2002 and 2010 were identified. The primary outcomes were the subsequent surgical treatment of SUI or POP. To compare the incidence with that of the general population, patients who had operative repair of a pelvic fracture were matched (1:2) to a person in the general population (with a propensity score to account for measurable potential confounders). Our primary analysis was a Cox proportional hazards model to compare hazard ratios (HR) in subjects with a pelvic fracture and those without.

RESULTS: We identified 390 female patients with a median age of 47 (IQR 30-67) years. Our median follow-up period was 5.9 (4.1-8.3) years. The absolute risk of SUI surgery after pelvic fracture was 3.3 % (13 out of 390) compared with 1.0 % (8 out of 769) in the matched general population sample. The HR for SUI surgery was 5.8 (95 % CI 2.2-15.1). The absolute risk of POP surgery after pelvic fracture was 1.8 % (7 out of 390) compared with 0.9 % (7 out of 769) in the matched general population. The HR for POP surgery was 2.3 (95 % CI 0.9-5.8).

CONCLUSIONS: Among patients who had a pelvic fracture requiring operative repair, there appears to be a significantly increased chance of surgery for SUI, but not for POP.

PMID: 25656453

Canada,Gender,Age,Predictive Risk Modeling,Post-operative Risk,Adult,Co-morbidity,Fractures,Bone/surgery,Middle Aged,Ontario/epidemiology,Pelvic Organ Prolapse/epidemiology,Pelvic Organ Prolapse/physio-pathology,Proportional Hazards Models,Retrospective Studies,Urinary Incontinence,Stress/epidemiology,Urinary Incontinence,Stress/physio-pathology

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